Antidepressants List

Up-to-date comprehensive listing includes most of the antidepressant medications in the current use. Caregorized by type (or biochemical family), generic names are listed first followed by the trade names.

Common features of all antidepressants:

  • 1. All antidepressants work by increasing the levels of neurotransmitters (chemical messengers) in the brain.
  • 2. Antidepressants are NOT controlled substances.
  • 3. Antidepressants improve depressive symptoms at about the same rate.

New Antidepressants

Generic Name Brand Name
Vortioxetine (serotonin modulator and stimulator) Brintellix, approved September 2013
Levomilnacipran (SNRI) Fetzima, approved July 2013
Vilazodone (SSRI) Viibryd, approved January 2011

SSRIs (Selective Serotonin Reuptake Inhibitors)

Generic Brand Name
Citalopram Celexa
Escitalopram Lexapro, Cipralex
Fluoxetine Prozac, Sarafem; Pexeva
Fluvoxamine Luvox
Paroxetine Paxil, Paxil CR
Sertraline Zoloft


Tricyclics (TCA)

Generic Brand Name
Amitriptyline Elavil, Endep, Levate
Amoxapine Asendin
Clomipramine Anafranil
Desipramine Norpramin, Pertofrane
Dosulepin Prothiaden, Thaden
Doxepin Adapin, Sinequan
Imipramine Tofranil
Lofepramine Gamanil, Lomont
Maprotiline Deprilept, Ludiomil, Psymion
Mianserin Bolvidon, Norval, Tolvan
Nortriptyline Pamelor
Protriptyline Vivactil
Trimipramine Surmontil

SNRIs (Serotonin and Noradrenaline Reuptake Inhibitors)

Generic Brand Name
Desvenlafaxine Pristiq
Duloxetine Cymbalta
Levomilnacipran Fetzima
Milnacipran Savella
Venlafaxine Effexor, Effexor XR

NaSSA (Noradrenergic and Specific Serotonergic Antidepressant)

Generic Brand Name
Mirtazapine Remeron, Remeron SolTab

NDRIs (Norepinephrine and Dopamine Reuptake Inhibitors)

Generic Brand Name
Bupropion Wellbutrin, Wellbutrin SR, Wellbutrin XL, Zyban; Aplenzin

Miscellaneous Antidepressants

Generic Brand Name
Atomoxetine (Norepinephrine reuptake Inhibitor) Strattera
Agomelatine (5-HT2C receptor antagonist) Valdoxan
(5HT1A receptor agonist)
(5HT2-receptor antagonist)
Nefadar, Serzone
Tandospirone (azapirone, 5HT1A receptor agonist) Sediel
(Serotonin reuptake enhancer)
(5HT2-receptor antagonist, triazolopyridine-derivative)
Desyrel, Apo-Trazodone, Oleptro
(Norepinephrine Reuptake Inhibitor)
Edronax, Vestra
Viloxazine (Norepinephrine Reuptake Inhibitor) Vivalan
(Selective serotonin reuptake inhibitor, Serotonin 5HT 1A receptor agonist)
Serotonin Modulator and Stimulator
Vortioxetine Brintellix
Etrafon, Triavil


MAOIs (Monoamine Oxidase Inhibitors)

Generic Brand Name
Isocarboxazid Marplan
Moclobemide Manerix
Phenelzine Nardil
Tranylcypromine Parnate
Selegiline Emsam (transdermal patch)

Mood Stabilizers

Some mood stabilizers used to treat depressive symptoms are:

Generic Brand Name
Lithium Eskalith, Lithane, Lithobid
Quetiapine Seroquel, Xeroquel, Ketipinor

Atypical antipsychotics

Certain atypical antipsychotics licensed to treat depression are:

Generic Brand Name
Brexpiprazole2 Rexulti


  • 1. New FDA Approved Drugs for Psychiatry/Psychology CenterWatch
  • 2. Rexulti (brexpiprazole) FDA approval FDA

Last reviewed: September 12, 2017


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