Drugs that may cause Epistaxis (Nosebleed) as a side effect



Drug Incidence
Abilify Tablets 1% or less
Accutane Capsules
Aceon Tablets (2 mg, 4 mg, 8 mg) 0.3% to 1%
Aciphex Tablets
Actiq 1% or greater
Activase I.V. Less than 1%
Adalat CC Tablets 3% or less
Advair Diskus 100/50 1% to 4%
Advair Diskus 250/50 1% to 4%
Advair Diskus 500/50 1% to 4%
AeroBid/AeroBid-M 1% to 3%
Aggrenox Capsules 2.4%
Agrylin Capsules 1% to 5%
Alferon N Injection 1%
Alinia for Oral Suspension Less than 1%
Altace Capsules Less than 1%
AmBisome for Injection 8.6% to 14.9%
Ambien Tablets Rare
Amerge Tablets Rare
Amnesteem Capsules
Anzemet Injection Rare
Anzemet Tablets Rare
Arava Tablets 1% to 3%
Aricept Tablets Infrequent
Astelin Nasal Spray 2% to 3.2%
Atacand HCT 0.5% or greater
Atacand Tablets 0.5% or greater
Atrovent Nasal Spray 0.03% 7% to 9%
Atrovent Nasal Spray 0.06% 8.2%
Avalide Tablets
Avapro Tablets Less than 1%
Axert Tablets Infrequent
Bactroban Nasal Less than 1%
Beconase AQ Nasal Spray Fewer than 3 per 100 patients
Bextra Tablets 0.1% to 1.9%
Busulfex I.V. 25%
Caduet Tablets Greater than 0.1% to less than 2%
Campath Ampules 1% to 7%
Campral Tablets Infrequent
Cardizem LA Extended-Release Tablets Less than 2%
Casodex Tablets 2% to 5%
Celebrex Capsules 0.1% to 1.9%
Celexa Infrequent
CellCept Capsules, Intravenous, Oral Suspension, Tablets 3% to less than 20%
Cialis Tablets Less than 2%
Cipro I.V. Pharmacy Bulk Package Less than 1%
Cipro I.V. 1% or less
Cipro XR Tablets
Cipro Less than 1%
Clinoril Tablets Less than 1%
Clozapine Tablets Less than 1%
Clozaril Tablets Less than 1%
Colazal Capsules
Copaxone for Injection Infrequent
Cosopt Sterile Ophthalmic Solution
Coumadin Tablets
Coumadin for Injection
Cozaar Tablets Less than 1%
DDAVP Nasal Spray Up to 3%
Depacon Injection 1% to 5%
Depakene 1% to 5%
Depakote ER Tablets 1% to 5%
Depakote Sprinkle Capsules 1% to 5%
Depakote Tablets 1% to 5%
Desmopressin Acetate Rhinal Tube Up to 3%
Diovan HCT Tablets Greater than 0.2%
Dostinex Tablets Less than 10%
Doxil Injection Less than 1%
DynaCirc CR Tablets 0.5% to 1%
Effexor Tablets Infrequent
Effexor XR Capsules Infrequent
Elidel Cream 1% Up to 3.3%
Elmiron Capsules Less than or equal to 1%
Eloxatin for Injection 2% to 9%
Evoxac Capsules 1% to 3%
Exelon Capsules Frequent
Exelon Oral Solution Frequent
FazaClo Orally Disintegrating Tablets Less than 1%
Flolan for Injection 4% to 9%
Flonase Nasal Spray 6% to 6.9%
Flovent Rotadisk 1% to 3%
Floxin Tablets Less than 1%
Fludara for Injection Up to 1%
Fortovase Capsules Less than 2%
Gabitril Tablets Frequent
Gamunex Immune Globulin I.V., 10% 23%
Gengraf Capsules 1% to less than 3%
Geodon Capsules Infrequent
Gleevec Tablets 3% to 12%
HIVID Tablets Less than 1%
Hytrin Capsules At least 1%
Hyzaar
Imitrex Nasal Spray
Indocin Capsules Less than 1%
Indocin I.V. Less than 1%
Indocin Less than 1%
Infergen 6% to 8%
Intal Inhaler Rare
Intron A for Injection Less than or equal to 5%
Invanz for Injection Greater than 0.1%
Invirase Capsules Less than 2%
Jantoven Tablets
Klonopin Infrequent
Lamictal Infrequent
Leukine 17%
Leustatin Injection 5%
Levaquin in 5% Dextrose Injection 0.1% to 1%
Levaquin 0.1% to 1%
Levitra Tablets Less than 2%
Lexapro Oral Solution Infrequent
Lexapro Tablets Infrequent
Lipitor Tablets Less than 2%
Lofibra Capsules Less than 1%
Lotensin HCT Tablets 0.3% or more
Lupron Depot-3 Month 22.5 mg Less than 5%
Lupron Depot-PED 7.5 mg, 11.25 mg and 15 mg Less than 2%
Lupron Injection Pediatric Less than 2%
Matulane Capsules
Mavik Tablets 0.3% to 1%
Maxalt Tablets Infrequent
Maxalt-MLT Orally Disintegrating Tablets Infrequent
Meridia Capsules
Merrem I.V. 0.2%
Miacalcin Nasal Spray 3.5%
Micardis HCT Tablets
Micardis Tablets More than 0.3%
Motrin Suspension, Oral Drops, Chewable Tablets, and Caplets Less than 1%
Mylotarg for Injection 3% to 34%
Nasacort AQ Nasal Spray 2.7%
Nasacort HFA Inhalation Aerosol Greater than or equal to 3%
Nasarel Nasal Spray 3% to 9%
Nasonex Nasal Spray 8% to 11%
Neoral Oral Solution 1% to less than 3%
Neoral Soft Gelatin Capsules 1% to less than 3%
Neupogen for Injection 9% to 15%
Neurontin Capsules Infrequent
Neurontin Oral Solution Infrequent
Neurontin Tablets Infrequent
Nexium Delayed-Release Capsules Less than 1%
Norvasc Tablets More than 0.1% to 1%
Norvir Less than 2%
Oncaspar Less than 1%
OptiPranolol Metipranolol Ophthalmic Solution 0.3% A small number of patients
Paxil CR Controlled-Release Tablets Infrequent
Paxil Infrequent
Permax Tablets 1.6%
Plavix Tablets 2.9%
Pletal Tablets Less than 2%
Prevacid Delayed-Release Capsules Less than 1%
Prevacid NapraPAC Less than 1%
Prevacid SoluTab Delayed-Release Orally Disintegrating Tablets Less than 1%
Prevacid for Delayed-Release Oral Suspension Less than 1%
Prevpac Less than 1%
Prilosec OTC Tablets Less than 1%
Prinivil Tablets 0.3% to 1%
Prinzide Tablets
ProSom Tablets Rare
Protonix I.V. Less than 1%
Protonix Ointment Greater than or equal to 1%
Protonix Tablets Less than 1%
Provigil Tablets 1%
Prozac Pulvules and Liquid Infrequent to greater than or equal to 2%
Pulmicort Respules 2% to 4%
Rapamune Oral Solution and Tablets 3% to 20%
Recombinate
Refludan for Injection 4.4%
Relenza Rotadisk Less than 1%
Relpax Tablets Rare
Reminyl Infrequent
ReoPro Vials 9 to 11 events
Requip Tablets Infrequent
Rescriptor Tablets
Retrovir Capsules
Retrovir I.V. Infusion
Retrovir
Rhinocort Aqua Nasal Spray 8%
Rilutek Tablets Infrequent
Risperdal Consta Injection Infrequent
Risperdal M-Tab Tablets Infrequent
Risperdal Infrequent
Rocephin Injectable Vials, ADD-Vantage, Galaxy, Bulk Rare
Roferon-A Injection Rare
Rythmol SR Capsules
Salagen Tablets 1% to 2%
Sandostatin Injection Less than 1%
Sandostatin LAR Depot 1% to 4%
Seroquel Tablets Infrequent
Sonata Capsules Less than 1%
Spiriva HandiHaler 1% to 4%
Sular Tablets Less than or equal to 1%
Symbyax Capsules Infrequent
TNKase I.V. 1.5%
Tamiflu Capsules 3.1%
Tamiflu Oral Suspension 3.1%
Tarka Tablets Less frequent
Tasmar Tablets Infrequent
Tequin Injection Less than 0.1%
Tequin Tablets Less than 0.1%
Teveten HCT Tablets Less than 1%
Teveten Tablets Less than 1%
Thalomid Capsules
Tiazac Capsules Less than 2%
Ticlid Tablets 0.5% to 1%
Tobi Solution for Inhalation 7%
Topamax Sprinkle Capsules 1% to 4%
Topamax Tablets 1% to 4%
Toradol 1% or less
Trental Tablets Less than 1%
Tricor Tablets
Trileptal Oral Suspension 2% to 4%
Trileptal Tablets 2% to 4%
Trisenox Injection 25%
Trusopt Sterile Ophthalmic Solution
Unasyn for Injection Less than 1%
Uniretic Tablets Less than 1%
VFEND I.V. Less than 1%
VFEND Oral Suspension Less than 1%
VFEND Tablets Less than 1%
Vantin Tablets and Oral Suspension Less than 1%
Viagra Tablets
Vioxx Greater than 0.1% to 1.9%
Wellbutrin Tablets Rare
Xanax XR Tablets Infrequent
Xeloda Tablets Less than 5%
Zegerid Powder for Oral Solution Less than 1%
Zevalin Injection 3%
Zoladex 3-month
Zoladex 1% or greater
Zoloft Infrequent to 2%
Zomig Nasal Spray Infrequent
Zomig Tablets Infrequent
Zomig-ZMT Tablets Infrequent
Zosyn 1% or less
Zyban Sustained-Release Tablets 2%
Zyprexa Tablets Infrequent
Zyprexa ZYDIS Orally Disintegrating Tablets Infrequent
Zyrtec Chewable Tablets 1.9% to 3.7%
Zyrtec-D 12 Hour Extended-Release Tablets 1.9% to 3.7%
Zyrtec 1.9% to 3.7%