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Trazodone Without a PrescriptionTrazodone hydrochloride, sold under the brand name Desyrel, is quite an old prescription antidepressant, that shares several properties of tricyclic antidepressants. It is widely prescribed for insomnia. Price consideration
Trazodone can be useful and cost-effective solution for insomniacs with depression or those who cannot take other RX options1. Although it is not FDA-approved for insomnia treatment, there is extensive clinical experience with this drug due to its sedative effect.
How to use
Trazodone is used in the treatment of major depression with or without prominent anxiety. It is particularly effective in reducing anxiety, tension, apathy, irritability, sleep disturbances and fatigue. Trazodone has a slightly more rapid onset of action than tricyclic antidepressants. Trazodone is sometimes used for the treatment of alcohol dependence. It can reduce symptoms during periods of intoxication and abstention. Trazodone may cause persistent, painful erection (known as priapism). It occurs in 0.1-0.01% of men who take this medicine. On the other hand, recent research suggests that the drug may help to produce an erection. So trazodone may be a reasnoble prescription choice for anxious or depressed men with erection problems. Precautions & contraindications It should not be used with sibutramine because very serious interaction may occur. It is also not recommended to be used during the initial recovery phase of myocardial infarction. Trazodone may impair the ability to perform activities requiring mental alertness or physical coordination. The sedative effects are enhanced by other central nervous system depressants such as alcohol, sedatives, and antidepressants. The most frequent side effects are constipation, dizziness, drowsiness, fatigue, headache, hypotension, and nausea. Dosage Depression: The initial dose is 150 mg/day in 3 divided doses. The dose may be increased by 50 mg/day every 3 to 4 days. The maximum daily dose usually should not exceed 400 mg. Insomnia: Unlike benzodiazepine sleep aids, trazodone may help insomnia without next day grogginess and sedation. Usually, the starting dose is 25-50 mg at bedtime. The dose can be increased if necessary up to 100 mg, and there is no need to take more. It's hypnotic effect starts within 1-2 hours and usually lasts about 8 hours. Taking trazodone in combination with other prescription medications, including MAO inhibitors, SSRI antidepressants, and triptans, may lead to serotonin syndrome. References
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