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Minocycline
Description
- Active ingredient: Minocycline
- Common brand names: Dynacin, Minocin, Vectrin
- Drug class: Tetracycline antibiotic
- Legal status: Prescription only
- Pregnancy Category: D
Minocycline uses:
- Anthrax (inhalational, cutaneous, and gastrointestinal)
- Acne
- Meningococcal (asymptomatic) carrier state
- Rickettsial diseases (including Rocky Mountain spotted fever, Q
fever)
- Nongonococcal urethritis
- Gonorrhea
- Syphilis
- Acute intestinal amebiasis
Dosage
- Usual dosage range:
Children >8 years: Initial: 4 mg/kg, followed by 2 mg/kg/dose every
12 hours
Adults: Initial: 200 mg, followed by 100 mg every 12 hours (maximum:
400 mg/day)
- Inflammatory Acne
Adults: 50 mg 1 to 3 times per day.
- Meningococcal Carrier State:
100 mg every 12 hr for 5 days.
- Primary/Secondary Syphilis:
200 mg initially then 100 mg every 12 hr for 10 to 15 days.
- Uncomplicated Gonococcal Urethritis in Men:
100 mg every 12 hr for 5 days.
- Dosage adjustment in renal impairment:
Consider decreasing dose or increasing dosing interval; total daily
dose should not exceed 200 mg
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